Boost NAD Levels with Nicotinamide Riboside

Are there any dietary restrictions?

TRU NIAGEN ® is vegetarian, gluten-free, nut-free, caffeine-free, contains no animal byproducts, and artificial colors or flavors.

Can I take TRU NIAGEN® with alcohol?

Yes, it is safe to take TRU NIAGEN® with alcohol. Alcohol is detoxified by enzymes that require NAD to function. The body uses nicotinamide riboside to make NAD, so NIAGEN® supplementation may be helpful in supporting a healthy liver.*

Can I take TRU NIAGEN® with my multivitamins?

Yes, it is safe to take TRU NIAGEN® while taking a standard multivitamin that provides the daily recommended amounts of vitamins, including those with vitamin B3. TRU NIAGEN® contains nicotinamide riboside which is not the same as the vitamin B3 sources found in multivitamin products. TRU NIAGEN® is absorbed by cells and efficiently converted to NAD using a unique pathway different from vitamin B3 (niacin, nicotinamide) found in vitamin supplements. TRU NIAGEN® has been extensively studied in clinical trials and proven safe and effective for increasing NAD.*

Multivitamins are designed to provide the daily recommended values for essential vitamins and minerals and are appropriately balanced so they don’t contain high doses of any one vitamin or mineral. Always check the label and consult your healthcare professional with any questions.

Can my child use TRU NIAGEN®?

TRU NIAGEN® is not intended for use by children. We recommend pregnant or nursing women to consult a physician. TRU NIAGEN® is safe when used as directed.

Has TRU NIAGEN® been tested for purity?

TRU NIAGEN® is manufactured in the U.S. under cGMP (current Good Manufacturing Practice) regulations enforced by the FDA. Our manufacturer is certified by the NSF, a leading independent public health and safety organization and each lot of TRU NIAGEN® undergoes thorough purity testing.

How does TRU NIAGEN® work?

While many factors contribute to aging, scientists believe one primary reason is the depletion of a key cellular resource called NAD. Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in every living cell and is as essential to those cells as water is to the body. But as we age, NAD levels decline. This natural decline may speed up anytime we eat too much, drink too much, work too much, stay in the sun for too long, don’t sleep well, or get sick.

Because NAD is essential to healthy cellular metabolism, the less we have of it, the harder it is for our cells to stay healthy as we age. But higher NAD levels have been linked to all kinds of positive health benefits.

In 2004, Charles Brenner PhD discovered a unique and overlooked form of vitamin B3 (nicotinamide riboside) that is a natural precursor to NAD. Meaning it helps our cells create more NAD and thereby helps them function better.

NIAGEN® is the first and only patented and safety tested form of nicotinamide riboside, and is proven to increase NAD levels.*

How does TRU NIAGEN® interact with Vitamin C or other amplifiers?

NIAGEN® helps your cells produce the coenzyme NAD which helps a cell’s mitochondria convert fat into fuel.* Vitamin C is essential to the synthesis of carnitine which shuttles fatty acids into the mitochondria for metabolism and ATP production.

Because both vitamin C and TRU NIAGEN® are important for cellular health and energy production, there is active research surrounding the exciting possibilities of TRU NIAGEN® working synergistically with vitamin C and other similar nutrients.*

How much research has been done on NIAGEN®?

A naturally-occurring, unique form of vitamin B3 known as nicotinamide riboside was first identified in the 1940s. This discovery came years after it was established that vitamin B3, in the common forms of niacin and niacinamide, could cure a disease caused by vitamin B3 deficiency known as pellagra.

Since that time, the role of nicotinamide riboside as a precursor to an essential coenzyme called NAD has been widely studied in the scientific community and become better understood. More than a decade of pre-clinical research has been conducted on nicotinamide riboside producing hundreds of research studies including a groundbreaking clinical study in 2016 proving NIAGEN® increases NAD levels in humans. These positive results have inspired research around the world. There are at least 14 additional clinical trials underway exploring the potential health benefits of NIAGEN®, the key ingredient in TRU NIAGEN®.

How much TRU NIAGEN® should I be taking?

Take two capsules of TRU NIAGEN® (125mg) every day with or without food. Each bottle contains a 30-day supply at this serving size.

Nicotinamide riboside and nicotine both contain nitrogen, but are otherwise completely unrelated. The two compounds do not share any physiological properties in the body.

Nicotinamide riboside is a unique form of vitamin B3 and a highly effective precursor to NAD. Nicotine is a highly addictive stimulant that comes from the tobacco plant. According to historical accounts, nicotine was named after a French ambassador, Jean Nicot, in the 16th century.

Is TRU NIAGEN® natural?

NIAGEN® is a nature-identical, synthesized form of a unique vitamin B3 known as nicotinamide riboside (NR). It is identical structurally and functionally to naturally-occurring NR found in trace amounts in milk.

Is TRU NIAGEN® safe?

Yes, TRU NIAGEN® is safe. Its sole active ingredient NIAGEN® has been rigorously tested using internationally accepted safety protocols, notified to the US Food and Drug Administration (FDA) as Generally Recognized As Safe (GRAS). NIAGEN® was also reviewed by FDA and listed as a New Dietary Ingredient. NIAGEN® is the first and only patented form of nicotinamide riboside to be reviewed by the FDA and granted these safety and dietary statuses.

What are the side effects?

No adverse effects attributed to the consumption of NIAGEN® were reported during our clinical trials. As with any form of supplementation, if you experience any prolonged discomfort or side effects, discontinue use and consult your healthcare provider.

What is NAD?

Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in every living cell. It’s essential to every cell but especially to those with mitochondria. That’s because the mitochondria are “the powerhouse of the cell.” Meaning that like any other battery or energy resource, the mitochondria depend on an external power source to keep them charged. NAD is that source.

With higher NAD levels, our cells can function at their best and so we can too.

What is the capsule made of?

Our vegetarian capsule is made of an FDA-approved food additive known as hypromellose. Hypromellose is a clear, transparent vegetarian alternative to gelatin capsules. [Note 21CFR 172.874]

What should I be expecting?

TRU NIAGEN’s sole active ingredient, NIAGEN, is proven to increase NAD levels in humans.* Higher NAD levels are linked to all kinds of positive benefits.

Your experience will vary depending on what your cellular needs are. But the science shows that TRU NIAGEN® is hard at work on a cellular level. And the longer you take it, the more opportunities you’ll have to feel those changes.*

What’s the difference between NIAGEN® and TRU NIAGEN®?

NIAGEN® is the first and only patented and safety-validated form of a unique and naturally occurring vitamin B3 known as nicotinamide riboside.

TRU NIAGEN® is the name of our product. Each capsule of TRU NIAGEN® contains 125mg of NIAGEN®.

Will my cells become dependent on TRU NIAGEN® and produce less NAD on their own?

Based on published research results, we have no reason to believe TRU NIAGEN® will decrease the natural activity level of enzymes that make NAD.